The Cultural Center Don Orione Artigianelli in Venice is a wide architectonic unit raised once as a monastery and later used as an orphanage and as a professional school. It is composed of four cloisters and several factory buildings, one different from the other according to typology and age of construction (XV – XX century). In the last few years the entire unit has been the subject of an articulated intervention of reconstruction and modernization that has dealt with the assignation of new use destinations according to the different areas: thanks to the works carried out between the years 1996 and 2006 it has been transformed in a Religious House for Hospitality and Congress Center. In order to realize all this, a scrupolous recovery intervention has been carried out aiming to preserve the oldest parts by taking the spatial characteristics of factories into consideration and at the same time caring about consolidating its structure, strengthening its garrets and the technological updating of the areas destinated to new functions. The oldest part, close to the Church, has been assigned to the residence of Fathers while the Congress Center and the Religious House for Hospitality are contained in the area dating back to the eighteenth century. In those areas that showed the necessity of brand new interventions, any ambiguous camouflage with the pre-existing materials has been avoided and so a planning of declaredly modern elements has been carried out like the new elliptic stairs, realized on a continuous structure of reinforced concrete left on sight that has been inserted in an existing space, the presence of which is underlined by the rhythm of holes. Along the paths, signs of the new planning are visible: enlightning bodies by the essential design, steel window and door frames and the sophisticated equipment for the functioning of congress rooms.